UTILIZING INTEGRATED BIOINFORMATICS AND MACHINE LEARNING APPROACHES TO ELUCIDATE BIOMARKERS LINKING SEPSIS TO FATTY ACID METABOLISM-ASSOCIATED GENES

Utilizing integrated bioinformatics and machine learning approaches to elucidate biomarkers linking sepsis to fatty acid metabolism-associated genes

Abstract Sepsis, characterized as a systemic inflammatory response triggered by the invasion of pathogens, represents a continuum that may escalate from mild systemic infection to severe sepsis, potentially resulting in septic shock and multiple organ dysfunction syndrome.Advancements in lipidomics and metabolomics have unveiled the complex role of

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Non-degradative Ubiquitination of Protein Kinases.

Growing evidence supports other regulatory roles for protein ubiquitination in addition to serving as a tag for proteasomal degradation.In contrast to other common post-translational modifications, such as phosphorylation, little is known about how non-degradative ubiquitination modulates protein structure, dynamics, and function.Due to the wealth

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A RES-GANomaly Method for Machine Sound Anomaly Detection

Automatic detection of mechanical failure is an essential technology in the fourth industrial revolution, which involves artificial-intelligence-based factory automation.The primary challenge in encoder-based machine sound anomaly detection lies in ensuring high-quality reconstruction of feature maps, as this directly impacts the precise definition

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Simultaneous evaluation of restless leg syndrome, neuropathic pain, disease activity, and quality of life in patients with Takayasu arteritis: a cross-sectional study

Abstract We aimed to investigate the frequency of restless legs syndrome (RLS) and neuropathic pain (NeP) in patients with Takayasu arteritis (TAK), and their relationship with disease activity, and quality of life (QoL).In this prospective case-control study, we evaluated 30 patients with TAK and 28 healthy subjects.Demographic, clinical, and curr

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Bifid Mandibular Condyle: A rare in plenty

The Patio Furniture bifid mandibular condyle has also been termed as Double Headed Condyle or Condylar Duplication.Bifid condyle was first reported by Hrdlicka in 1941.Since then, to the best of our knowledge, about 49 cases of bifid condyle have been reported in medical literature.We Transfer Belt Kit present here six cases of bifid mandibular con

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